Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.31 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809857 | 0.85 | HDAC4 (0.32) | CYP2C9 | |
| SCHEMBL7401494 | 0.83 | CYP2C9 (0.36) | CYP2C9VKORC1MGAMGAASI | |
| SCHEMBL8807704 | 0.81 | ALOX12 (0.33) | — | |
| SCHEMBL7406127 | 0.80 | MAPT (0.31) | MAPT | |
| SCHEMBL6177695 | 0.79 | CYP2C9 (0.38) | CYP2C9VKORC1MAPT | |
| SCHEMBL6176046 | 0.79 | — | — | |
| SCHEMBL8807412 | 0.79 | METAP2 (0.35) | MAPTGAA | |
| SCHEMBL7401490 | 0.78 | — | — | |
| SCHEMBL8805562 | 0.78 | BRAF (0.31) | — | |
| SCHEMBL8807112 | 0.77 | KDM1A (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758327-A1 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-19 | — | — | EP | disclosed |