Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806888 | 0.96 | ACHE (0.53) | ACHEKDM4EALDH1A1HPGDRXFP1 | |
| SCHEMBL8808311 | 0.95 | ACHE (0.54) | ACHEBCHE | |
| SCHEMBL8807166 | 0.94 | ACHE (0.53) | ACHEBCHE | |
| SCHEMBL8808418 | 0.94 | ACHE (0.56) | ACHEKDM4EALDH1A1HPGDRXFP1 | |
| SCHEMBL8807067 | 0.85 | ACHE (0.53) | ACHEKDM4EALDH1A1HPGDRXFP1 | |
| SCHEMBL8809511 | 0.83 | ACHE (0.70) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL8808991 | 0.83 | EGFR (0.52) | ACHE | |
| SCHEMBL8810369 | 0.81 | DRD2 (0.56) | ACHEBCHE | |
| SCHEMBL8809835 | 0.80 | BCHE (0.54) | ACHEBCHE | |
| SCHEMBL8808462 | 0.80 | DRD2 (0.54) | ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584091-B1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-5428038-A | Administering for preventing or treating N-methyl-D-aspartate induced convulsions | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1995-06-27 | — | — | US | disclosed |