Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.42 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.42 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806198 | 0.86 | ALDH1A1 (0.44) | THRBALDH1A1GAACACNB4CACNA1A | |
| SCHEMBL7493208 | 0.86 | SLC10A2 (0.50) | SLC10A2THRBALDH1A1GAACACNB4 | |
| SCHEMBL7485921 | 0.85 | SLC10A2 (0.48) | SLC10A2THRBALDH1A1GAACACNB4 | |
| SCHEMBL7688481 | 0.85 | SLC10A2 (0.42) | SLC10A2ALDH1A1GAACACNB4CACNA1A | |
| SCHEMBL8607921 | 0.82 | SLC10A2 (0.51) | SLC10A2ALDH1A1GAACACNB4CACNA1A | |
| SCHEMBL7493393 | 0.82 | SLC10A2 (0.47) | SLC10A2THRBALDH1A1GAACACNB4 | |
| Diethylamine SCHEMBL7485928 | 0.79 | ABCG2 (0.54) | SLC10A2THRBALDH1A1GAACACNB4 | |
| SCHEMBL8610400 | 0.79 | ALDH1A1 (0.49) | SLC10A2ALDH1A1GAACACNB4CACNA1A | |
| SCHEMBL7494921 | 0.79 | SLC10A2 (0.44) | SLC10A2THRBALDH1A1GAACACNB4 | |
| SCHEMBL8609865 | 0.77 | SLC10A2 (0.48) | SLC10A2THRBALDH1A1GAACACNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014319-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |