Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681469 | 0.93 | OPRD1 (0.49) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| SCHEMBL6601536 | 0.91 | KDM4E (0.64) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| SCHEMBL9776407 | 0.89 | LMNA (0.51) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| SCHEMBL13504067 | 0.88 | OPRD1 (0.46) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| SCHEMBL6160138 | 0.88 | SLC6A4 (0.54) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| SCHEMBL4753533 | 0.88 | CHRM3 (0.58) | CHRM3CHRM2OPRD1OPRM1SIGMAR1 | |
| SCHEMBL6160130 | 0.88 | OPRD1 (0.51) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL22797859 | 0.86 | SLC6A2 (0.53) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| SCHEMBL28891615 | 0.83 | MEN1 (0.54) | CHRM3CHRM2OPRD1LMNAALDH1A1 | |
| SCHEMBL14507949 | 0.82 | CHRM3 (0.53) | CHRM3CHRM2OPRD1ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603627-B | Synthesis method of pyrrolidone spiro-propane compound | 江西省科学院应用化学研究所 | 2023-08-18 | — | — | CN | disclosed |
| EP-0755384-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028391-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |