Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL9833807 | 0.73 | ALOX5 (0.55) | ALOX5 | |
| Tetrabuthylammonium SCHEMBL9764880 | 0.72 | NPC1 (0.44) | ALOX5 | |
| SCHEMBL8806923 | 0.67 | ALOX5 (0.73) | ALOX5 | |
| Tetrabuthylammonium SCHEMBL28209653 | 0.64 | SLC22A1 (0.67) | — | |
| SCHEMBL8806895 | 0.64 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8807571 | 0.64 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9473684 | 0.63 | ALOX5 (0.65) | ALOX5 | |
| Tetrabuthylammonium SCHEMBL28226462 | 0.62 | SLC22A1 (0.63) | — | |
| Tetrabuthylammonium SCHEMBL28259665 | 0.62 | SLC22A1 (0.63) | — | |
| Tetrabuthylammonium SCHEMBL29113226 | 0.62 | SLC22A1 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320628-B1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5112848-A | Antiasthmatics and antiarthritic agents | ABBOTT LABORATORIES (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0320628-A1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LABORATORIES (US) | 1989-06-21 | — | — | EP | disclosed |