⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807303 | 0.77 | — | — | |
| SCHEMBL23489621 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL25427811 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL4591310 | 0.65 | — | — | |
| SCHEMBL8808010 | 0.64 | MEN1 (0.35) | — | |
| SCHEMBL9509472 | 0.63 | — | — | |
| SCHEMBL11450561 | 0.61 | — | — | |
| SCHEMBL25278809 | 0.61 | — | — | |
| SCHEMBL8806119 | 0.58 | CYP3A4 (0.30) | — | |
| SCHEMBL25308474 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476456-B1 | Substituted 2-thiazolyl tetrazolium salt indicators | BAYER AG (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0476454-B1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | BAYER AG (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5322680-A | Chromogenic detector for medical diagnosis by forming formazan dyes chemical reduction | MILES INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0432563-B1 | 4-Substituted-5-chloro-2-hydrazino thiazols | BAYER AG (DE) | 1994-03-09 | — | — | EP | disclosed |
| US-5126275-A | Chromogenic reducing indicators for reducing substances such as NADH | MILES INC. (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0476454-A1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | Bayer Corporation (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476456-A2 | Substituted 2-thiazolyl tetrazolium salt indicators | Bayer Corporation (US) | 1992-03-25 | — | — | EP | disclosed |
| US-5068343-A | Fungicides for plants | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0432563-A2 | 4-Substituted-5-chloro-2-hydrazino thiazols | BAYER AG (DE) | 1991-06-19 | — | — | EP | disclosed |