Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073804 | 0.93 | MAPT (0.39) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL8807303 | 0.83 | — | — | |
| SCHEMBL8807352 | 0.64 | — | — | |
| SCHEMBL3810678 | 0.63 | MAPT (0.39) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL3817613 | 0.59 | GAA (0.43) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL23489621 | 0.59 | ALDH1A1 (0.32) | ALDH1A1HPGD | |
| SCHEMBL25427811 | 0.58 | KMT2A (0.32) | KMT2AALDH1A1 | |
| SCHEMBL9505500 | 0.54 | — | — | |
| SCHEMBL4591310 | 0.53 | — | — | |
| SCHEMBL9505486 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476456-B1 | Substituted 2-thiazolyl tetrazolium salt indicators | BAYER AG (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5322680-A | Chromogenic detector for medical diagnosis by forming formazan dyes chemical reduction | MILES INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0476456-A2 | Substituted 2-thiazolyl tetrazolium salt indicators | Bayer Corporation (US) | 1992-03-25 | — | — | EP | disclosed |