Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | VSIR | Q9H7M9 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809534 | 0.88 | CHEK1 (0.51) | CHEK1ROCK2NPY5RPOLBRAB9A | |
| SCHEMBL1773863 | 0.78 | RAB9A (0.61) | CHEK1POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL8815388 | 0.77 | PARP1 (0.51) | POLBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28282909 | 0.74 | RAB9A (0.57) | CHEK1POLBRAB9AKDM4EALDH1A1 | |
| SCHEMBL4893890 | 0.74 | RAB9A (0.57) | POLBRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22000113 | 0.74 | BCHE (0.55) | BCHEKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8808211 | 0.73 | BCHE (0.42) | BCHEVSIRBRD4KDM4EALDH1A1 | |
| SCHEMBL8810148 | 0.73 | BCHE (0.42) | BCHEVSIRBRD4KDM4EALDH1A1 | |
| SCHEMBL20465066 | 0.73 | NOTUM (0.51) | NPY5RPOLBRAB9AALDH1A1SMN1; SMN2 | |
| Boric Acid SCHEMBL8816030 | 0.72 | RAB9A (0.53) | POLBRAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |