Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808211 | 0.81 | BCHE (0.42) | BCHEKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2449809 | 0.77 | ALOX15 (0.48) | KDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15186428 | 0.75 | CYP4F2 (0.44) | — | |
| SCHEMBL6850959 | 0.74 | IDO1 (0.46) | SMN1; SMN2 | |
| SCHEMBL8812099 | 0.74 | SMN1; SMN2 (0.39) | BCHEKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8807533 | 0.73 | CHEK1 (0.41) | BCHEKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22000113 | 0.73 | BCHE (0.55) | BCHEKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8811307 | 0.72 | BCHE (0.45) | BCHEKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6846877 | 0.71 | IKBKE (0.46) | ALDH1A1 | |
| SCHEMBL15186334 | 0.70 | LRRK2 (0.52) | KDM4EALDH1A1HTTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |