Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CASR | P41180 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808116 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AALDH1A1MITFLMNA | |
| SCHEMBL8694072 | 0.91 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2AALDH1A1LMNAHTT | |
| SCHEMBL8499037 | 0.91 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2AALDH1A1LMNAHTT | |
| SCHEMBL19570479 | 0.91 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2AALDH1A1MITFLMNA | |
| SCHEMBL5270611 | 0.83 | BCHE (0.59) | SMN1; SMN2KMT2AALDH1A1MITFLMNA | |
| SCHEMBL14469578 | 0.82 | SMN1; SMN2 (0.82) | SMN1; SMN2KMT2AALDH1A1LMNAHTT | |
| SCHEMBL6142841 | 0.81 | CASR (0.75) | SMN1; SMN2KMT2AALDH1A1MITFLMNA | |
| SCHEMBL1162780 | 0.81 | CASR (0.75) | SMN1; SMN2KMT2AALDH1A1MITFLMNA | |
| SCHEMBL5270710 | 0.80 | LTA4H (0.48) | SMN1; SMN2KMT2AALDH1A1HTTLTA4H | |
| SCHEMBL29560 | 0.79 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |