Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811827 | 0.81 | HRH3 (0.54) | HRH3POLBHDAC1KDM4EALDH1A1 | |
| SCHEMBL10953965 | 0.76 | HRH3 (0.88) | HRH3POLBHDAC1KDM4EALDH1A1 | |
| SCHEMBL8810497 | 0.75 | HRH3 (0.54) | HRH3POLBKDM4EALDH1A1PKM | |
| SCHEMBL8810828 | 0.75 | HRH3 (0.62) | HRH3POLBACHEHDAC1KDM4E | |
| SCHEMBL8818072 | 0.74 | HRH3 (0.60) | HRH3POLBACHEHDAC1KDM4E | |
| SCHEMBL28658862 | 0.73 | RAD52 (0.42) | HRH3KDM4EALDH1A1GAA | |
| SCHEMBL19650814 | 0.72 | BRD4 (0.50) | HRH3ACHEKDM4EALDH1A1BACE1 | |
| SCHEMBL5863714 | 0.72 | POLB (0.93) | HRH3POLBACHEHDAC1BACE1 | |
| SCHEMBL3862351 | 0.72 | HRH3 (0.72) | HRH3POLBACHEHDAC1KDM4E | |
| SCHEMBL17335877 | 0.72 | HRH3 (0.72) | HRH3POLBHDAC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |