Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | VHL | P40337 | 1/20 | 0.44 |
| ▸ | ELOC | Q15369 | 1/20 | 0.44 |
| ▸ | ELOB | Q15370 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807545 | 0.83 | ALDH1A1 (0.54) | HRH3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL10953965 | 0.82 | HRH3 (0.88) | HRH3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL8808479 | 0.81 | HRH3 (0.54) | HRH3POLBALDH1A1LMNAHDAC1 | |
| SCHEMBL8811827 | 0.78 | HRH3 (0.54) | HRH3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL24574127 | 0.77 | HRH3 (0.71) | HRH3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL294763 | 0.77 | HRH3 (0.71) | HRH3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL10789534 | 0.77 | HRH3 (0.71) | HRH3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL1847296 | 0.77 | HRH3 (0.71) | HRH3POLBALDH1A1MEN1KMT2A | |
| SCHEMBL8818072 | 0.76 | HRH3 (0.60) | HRH3POLBALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11782513 | 0.75 | HRH3 (0.69) | HRH3POLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |