Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808078 | 0.85 | CRBN (0.44) | CRBNMMP1MMP9MAOAMAOB | |
| SCHEMBL9197046 | 0.81 | MMP1 (0.43) | CRBNMMP1MMP9DAOALDH1A1 | |
| SCHEMBL9201296 | 0.78 | CRBN (0.41) | CRBNMMP1MMP9DAOALDH1A1 | |
| SCHEMBL9196923 | 0.78 | CRBN (0.41) | CRBNMMP1MMP9DAOALDH1A1 | |
| SCHEMBL8810304 | 0.75 | CRBN (0.37) | CRBNMMP1DAOALDH1A1TSHR | |
| SCHEMBL9369558 | 0.75 | CRBN (0.48) | CRBNMMP1MMP9MAOAMAOB | |
| SCHEMBL9199499 | 0.74 | FABP7 (0.47) | MMP1MMP9TSHRMMP13MEN1 | |
| SCHEMBL8441916 | 0.73 | CRBN (0.48) | CRBNMMP1MMP9MAOAMAOB | |
| SCHEMBL8441175 | 0.70 | MAOA (0.45) | CRBNMMP1MMP9MAOAMAOB | |
| SCHEMBL9195547 | 0.69 | IDO1 (0.43) | CRBNMMP1DAOALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557122-B1 | A production method for sulfamide | SHIONOGI & CO (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5539102-A | ANTIBIOTIC SYNTHESIS BY DEHYDRATION REACTION OF ALCOHOL WITH OXYCARBONYLSULFAMIDE IN THE PRESENCE OF TRIVALENT PHOSPHOROUS | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0557122-A1 | A production method for sulfamide | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |