Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226916 | 0.77 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL5866499 | 0.77 | NR4A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL31083578 | 0.77 | NR4A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL30998134 | 0.75 | MAPT (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA2 | |
| SCHEMBL29589251 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL5030886 | 0.75 | MAPT (0.54) | ALDH1A1KDM4EHPGDHSD17B10CA2 | |
| SCHEMBL300219 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL31626799 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL25871284 | 0.75 | CA2 (0.48) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL4103770 | 0.74 | CDC25B (0.68) | ALDH1A1KDM4EHPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |
| EP-0649410-A1 | ANILIDE DERIVATIVES. | GLAXO LAB SA (FR) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001408-A1 | ANILIDE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1994-01-20 | — | — | WO | disclosed |