Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810059 | 0.97 | PDE4A (0.32) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8809231 | 0.87 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DPDK2 | |
| SCHEMBL8812180 | 0.84 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DPDK2 | |
| SCHEMBL8810186 | 0.83 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8810026 | 0.80 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8811749 | 0.80 | AKR1C3 (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8810775 | 0.78 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DPDK2 | |
| SCHEMBL8807574 | 0.78 | BACE1 (0.37) | PDE4APDE4BPDE4CPDE4DPDK2 | |
| SCHEMBL8809838 | 0.78 | ALDH1A1 (0.36) | PDE4APDE4BPDE4CPDE4DPDK2 | |
| SCHEMBL9138225 | 0.78 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350805-B1 | Benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds | BEIERSDORF LILLY GMBH (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5096914-A | Hypotensive agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5028711-A | Hypotensive Agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |