Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812750 | 0.97 | AKR1C3 (0.34) | AKR1C3SMN1; SMN2LMNATP53PDE4A | |
| SCHEMBL8809838 | 0.87 | ALDH1A1 (0.36) | AKR1C3SMN1; SMN2LMNATP53PDE4A | |
| SCHEMBL8807323 | 0.84 | LMNA (0.36) | AKR1C3SMN1; SMN2LMNAPDE4APDE4B | |
| SCHEMBL8813241 | 0.83 | LMNA (0.35) | AKR1C3SMN1; SMN2LMNATP53PDE4A | |
| SCHEMBL27406404 | 0.81 | KDM4E (0.42) | AKR1C3SMN1; SMN2LMNAPDE4APDE4B | |
| SCHEMBL8809602 | 0.80 | PDE4A (0.34) | AKR1C3SMN1; SMN2LMNAPDE4APDE4B | |
| SCHEMBL8808152 | 0.80 | PDE4A (0.32) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8807574 | 0.79 | BACE1 (0.37) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8810775 | 0.79 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9138225 | 0.79 | PDE4A (0.34) | LMNAPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350805-B1 | Benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds | BEIERSDORF LILLY GMBH (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5096914-A | Hypotensive agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5028711-A | Hypotensive Agents | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |