Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809430 | 1.00 | MAPT (0.48) | MAPTTP53ABCG2RXFP1MEN1 | |
| SCHEMBL8810999 | 0.86 | SLC6A5 (0.44) | MAPTTP53RXFP1MEN1KMT2A | |
| SCHEMBL8808197 | 0.86 | ABCG2 (0.46) | MAPTTP53ABCG2RXFP1MEN1 | |
| SCHEMBL8809423 | 0.85 | ACKR3 (0.45) | MAPTTP53ABCG2MEN1KMT2A | |
| SCHEMBL8810848 | 0.85 | MAPT (0.44) | MAPTTP53RXFP1MEN1KMT2A | |
| SCHEMBL8788917 | 0.81 | ABCG2 (0.72) | MAPTTP53ABCG2MEN1KMT2A | |
| SCHEMBL8790131 | 0.81 | ABCG2 (0.72) | MAPTTP53ABCG2MEN1KMT2A | |
| SCHEMBL8809638 | 0.79 | F10 (0.42) | MAPTTP53ABCG2MEN1KMT2A | |
| SCHEMBL8809649 | 0.79 | MAPT (0.40) | MAPTTP53ABCG2MEN1KMT2A | |
| SCHEMBL8807018 | 0.79 | MAPT (0.42) | MAPTTP53ABCG2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |