Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809423 | 0.91 | ACKR3 (0.45) | ABCG2MAPTTP53MEN1KMT2A | |
| SCHEMBL8808386 | 0.90 | MAPT (0.45) | ABCG2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8807015 | 0.87 | ABCG2 (0.44) | ABCG2MAPTTP53MEN1KMT2A | |
| SCHEMBL8807951 | 0.86 | BCHE (0.45) | ABCG2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8807068 | 0.86 | KCNH2 (0.44) | ABCG2MAPTTP53MEN1KMT2A | |
| SCHEMBL8809430 | 0.86 | MAPT (0.48) | ABCG2MAPTTP53MEN1KMT2A | |
| SCHEMBL8808205 | 0.86 | MAPT (0.48) | ABCG2MAPTTP53MEN1KMT2A | |
| SCHEMBL8808236 | 0.86 | MAPT (0.45) | ABCG2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL8807954 | 0.85 | F10 (0.43) | ABCG2MAPTTP53MEN1KMT2A | |
| SCHEMBL8809638 | 0.82 | F10 (0.42) | ABCG2MAPTTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |