Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 6/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.58 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202774 | 1.00 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6783780 | 0.92 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL6784471 | 0.91 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6786031 | 0.87 | GRIA1 (0.64) | GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL8813106 | 0.86 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7959740 | 0.81 | GRIA1 (0.87) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6785459 | 0.81 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6785960 | 0.80 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8810839 | 0.79 | GRIA1 (0.87) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7103867 | 0.78 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664807-B1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS | WARNER LAMBERT CO (US) | 1997-09-10 | — | — | EP | claimed |