Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810117 | 0.96 | MCHR1 (0.45) | MAOAMAOBACHEKDROPRM1 | |
| SCHEMBL8808236 | 0.93 | MAPT (0.45) | MAOAMAOBKDR | |
| SCHEMBL8809632 | 0.92 | BCHE (0.44) | MAOBACHEOPRM1TMEM97SIGMAR1 | |
| SCHEMBL8809566 | 0.91 | BCHE (0.43) | MAOAMAOBACHEOPRM1TMEM97 | |
| SCHEMBL8808101 | 0.90 | BCHE (0.43) | MAOAMAOBACHEOPRM1TMEM97 | |
| SCHEMBL8807951 | 0.90 | BCHE (0.45) | ACHEOPRM1TMEM97SIGMAR1BCHE | |
| SCHEMBL8809362 | 0.90 | SMN1; SMN2 (0.43) | MAOAMAOBACHEOPRM1TMEM97 | |
| SCHEMBL8807068 | 0.89 | KCNH2 (0.44) | KDR | |
| SCHEMBL8808371 | 0.88 | KDR (0.46) | MAOAMAOBKDR | |
| SCHEMBL8807015 | 0.85 | ABCG2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |