Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406532 | 0.86 | EPHX1 (0.38) | CAPN1CAPNS1EPHX1TSHRCYP3A4 | |
| SCHEMBL8812318 | 0.84 | CTSK (0.40) | CAPN1CAPNS1CTSLCTSSCTSK | |
| SCHEMBL8808483 | 0.82 | CAPN1 (0.51) | CAPN1CAPNS1HDAC4HDAC1EDNRA | |
| SCHEMBL8808493 | 0.82 | CAPN1 (0.51) | CAPN1CAPNS1HDAC4HDAC1EDNRA | |
| SCHEMBL8404241 | 0.80 | CAPN1 (0.38) | CAPN1CAPNS1EPHX1SMN1; SMN2 | |
| SCHEMBL8408035 | 0.80 | CAPN1 (0.38) | CAPN1CAPNS1EPHX1SMN1; SMN2 | |
| SCHEMBL8404294 | 0.80 | CAPN1 (0.38) | CAPN1CAPNS1EPHX1SMN1; SMN2 | |
| SCHEMBL8406495 | 0.79 | CAPN1 (0.51) | CAPN1CAPNS1CYP1A2CTSLCTSS | |
| SCHEMBL8811439 | 0.77 | CAPN1 (0.44) | CAPN1CAPNS1CYP1A2CTSLCTSS | |
| SCHEMBL8810066 | 0.76 | CAPN1 (0.47) | CAPN1CAPNS1CYP2C19LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |