Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808344 | 0.96 | ACHE (0.49) | MAPTKDRMAOBADORA2BACHE | |
| SCHEMBL8815521 | 0.93 | ACHE (0.52) | MAPTKDRACHEBCHEKDM4E | |
| SCHEMBL8831005 | 0.91 | MAPT (0.49) | MAPTKDRMAOBADORA2BMCHR1 | |
| SCHEMBL8807556 | 0.89 | MAOB (0.47) | MAPTMAOBADORA2BMEN1KMT2A | |
| SCHEMBL8815533 | 0.87 | KDR (0.48) | MAPTKDRMAOBADORA2BMCHR1 | |
| SCHEMBL8807068 | 0.83 | KCNH2 (0.44) | MAPTKDRMEN1KMT2ATP53 | |
| SCHEMBL8789872 | 0.83 | ABCG2 (0.57) | MAPTKDRMEN1KMT2AABCB1 | |
| SCHEMBL8808731 | 0.83 | MAPT (0.48) | MAPTMAOBADORA2BMCHR1MEN1 | |
| SCHEMBL8789875 | 0.83 | SMPD1 (0.45) | MAPTKDRABCB1TP53KDM4E | |
| SCHEMBL8808353 | 0.82 | MAPT (0.47) | MAPTMAOBADORA2BMCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |