Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 7/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810078 | 0.91 | CSNK2A2 (0.45) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8809369 | 0.90 | SLC2A1 (0.46) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8811097 | 0.89 | PARP1 (0.58) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8808793 | 0.88 | PARP1 (0.60) | PARP1HPGDPIM1AKR1B1PIM2 | |
| SCHEMBL8691075 | 0.88 | PARP1 (0.60) | PARP1HPGDPIM1AKR1B1PIM2 | |
| SCHEMBL8813934 | 0.88 | PARP1 (0.48) | PARP1MAPTALDH1A1 | |
| SCHEMBL8812081 | 0.87 | PARP1 (0.46) | PARP1LMNAPIM1NPC1RAB9A | |
| SCHEMBL8810812 | 0.87 | PARP1 (0.42) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8685967 | 0.87 | PARP1 (0.50) | PARP1MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL8811687 | 0.87 | PARP1 (0.58) | PARP1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |