Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | LPO | P22079 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810078 | 0.93 | CSNK2A2 (0.45) | SLC2A1PARP1CSNK2A2CLK1CSNK2B | |
| SCHEMBL8808802 | 0.90 | CSNK2A2 (0.51) | PARP1CSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8809361 | 0.89 | PARP1 (0.58) | SLC2A1PARP1PIM1AKR1B1PIM2 | |
| SCHEMBL8810641 | 0.89 | PARP1 (0.58) | PARP1CSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8685971 | 0.89 | PARP1 (0.58) | SLC2A1PARP1PIM1AKR1B1PIM2 | |
| SCHEMBL8810812 | 0.88 | PARP1 (0.42) | PARP1CSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8809171 | 0.87 | PARP1 (0.48) | SLC2A1PARP1MAPTLMNATP53 | |
| SCHEMBL8813170 | 0.86 | CSNK2A2 (0.44) | PARP1CSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8814237 | 0.86 | CSNK2A2 (0.44) | PARP1CSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8685967 | 0.86 | PARP1 (0.50) | PARP1MAPTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |