Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 15/20 | 0.50 |
| ▸ | CAPNS1 | P04632 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809572 | 0.83 | CAPN1 (0.50) | CAPN1CAPNS1CCR1 | |
| SCHEMBL8809102 | 0.82 | CAPN1 (0.69) | CAPN1CAPNS1 | |
| SCHEMBL8404287 | 0.82 | CAPN1 (0.51) | CAPN1CYP1A2 | |
| SCHEMBL8809091 | 0.82 | CAPN1 (0.69) | CAPN1CAPNS1 | |
| SCHEMBL8812110 | 0.80 | CAPN1 (0.46) | CAPN1ALDH1A1LMNA | |
| SCHEMBL8810652 | 0.80 | CAPN1 (0.48) | CAPN1CAPNS1CYP1A2 | |
| SCHEMBL8807996 | 0.78 | CAPN1 (0.50) | CAPN1CAPNS1CCR1 | |
| SCHEMBL8808452 | 0.77 | MEN1 (0.48) | CAPN1CAPNS1ALDH1A1TSHR | |
| SCHEMBL8407418 | 0.77 | CAPN1 (0.47) | CAPN1CAPNS1LMNA | |
| SCHEMBL8815203 | 0.77 | CAPN1 (0.39) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |