Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 11/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407710 | 0.91 | CAPN1 (0.47) | CAPN1CASP1CASP3CASP7CASP6 | |
| SCHEMBL8811002 | 0.90 | CAPN1 (0.48) | CAPN1CASP1CASP3CASP7CASP6 | |
| SCHEMBL8808872 | 0.90 | CTSK (0.43) | CAPN1CASP1CASP3CASP7CASP6 | |
| SCHEMBL8809745 | 0.89 | CAPN1 (0.50) | CAPN1CASP1CASP3CASP7CASP6 | |
| SCHEMBL8808402 | 0.89 | CAPN1 (0.46) | CAPN1CASP1CASP3CASP7CASP6 | |
| SCHEMBL8810857 | 0.88 | CAPN1 (0.49) | CAPN1CASP1CASP3CASP7CASP6 | |
| SCHEMBL8406495 | 0.87 | CAPN1 (0.51) | CAPN1CTSKCTSSCTSLPSMB1 | |
| SCHEMBL8407723 | 0.86 | CYP1A2 (0.43) | CAPN1CASP3CTSSCYP1A2 | |
| SCHEMBL8810894 | 0.85 | CAPN1 (0.41) | CAPN1 | |
| SCHEMBL8810652 | 0.85 | CAPN1 (0.48) | CAPN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |