SCHEMBL8810652

SCHEMBL8810652

CC(C)C[C@H](CN[C@H]1CCOC1O)NC(=O)Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 19/20 0.48
CAPNS1 P04632 6/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8404287 0.85 CAPN1 (0.51) CAPN1CYP1A2
SCHEMBL8809572 0.84 CAPN1 (0.50) CAPN1CAPNS1
SCHEMBL8807293 0.83 CAPN1 (0.42) CAPN1CAPNS1
SCHEMBL8810647 0.82 CAPN1 (0.67) CAPN1CAPNS1
SCHEMBL8810659 0.82 CAPN1 (0.67) CAPN1CAPNS1
SCHEMBL8810857 0.82 CAPN1 (0.49) CAPN1CAPNS1CYP1A2
SCHEMBL8809665 0.80 CAPN1 (0.42) CAPN1
SCHEMBL8407723 0.80 CYP1A2 (0.43) CAPN1CAPNS1CYP1A2
SCHEMBL8809095 0.80 CAPN1 (0.50) CAPN1CAPNS1CYP1A2
SCHEMBL8810844 0.80 SMN1; SMN2 (0.39) CAPN1CAPNS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810221-A1 OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-03 EP disclosed