Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461703 | 0.89 | SLC6A2 (0.59) | HTR2AHRH3SLC6A2SLC6A4DRD3 | |
| SCHEMBL466855 | 0.89 | HRH3 (0.71) | HTR2AHRH3HTR2CHTR7CYP2D6 | |
| Water SCHEMBL10460336 | 0.88 | SLC6A2 (0.58) | HTR2AHRH3SLC6A2SLC6A4DRD3 | |
| SCHEMBL10560292 | 0.84 | SLC6A2 (0.63) | HRH3SLC6A2SLC6A4DRD3 | |
| SCHEMBL11358816 | 0.84 | HTR2A (0.60) | HTR2AHTR2CHTR7CYP2D6DRD3 | |
| SCHEMBL8808110 | 0.83 | HTR2A (0.60) | HTR2AHRH3HTR2CHTR7CYP2D6 | |
| Hydrochloric Acid SCHEMBL7253239 | 0.82 | HTR2A (0.64) | HTR2AHRH3HTR2CHTR7CYP2D6 | |
| SCHEMBL8808087 | 0.82 | HTR2A (0.53) | HTR2AHRH3HTR2CHTR7CYP2D6 | |
| Oxalic Acid SCHEMBL10460396 | 0.81 | SLC6A2 (0.56) | HRH3SLC6A2SLC6A4DRD3 | |
| Hydrochloric Acid SCHEMBL7413630 | 0.79 | SLC6A2 (0.48) | HTR2AHRH3SLC6A2SLC6A4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751936-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025721-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-09-28 | — | — | WO | disclosed |