Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 5/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560292 | 0.94 | SLC6A2 (0.63) | SLC6A2SLC6A4DRD2SLC6A3HRH3 | |
| Oxalic Acid SCHEMBL10460451 | 0.90 | DRD2 (0.60) | SLC6A2SLC6A4DRD2SLC6A3KDM4E | |
| SCHEMBL10461703 | 0.89 | SLC6A2 (0.59) | SLC6A2SLC6A4DRD2HRH3DRD3 | |
| Water SCHEMBL10460336 | 0.88 | SLC6A2 (0.58) | SLC6A2SLC6A4DRD2HRH3DRD3 | |
| Oxalic Acid SCHEMBL10461397 | 0.84 | KDM4E (0.58) | DRD2MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL10560791 | 0.84 | DRD2 (0.57) | SLC6A2SLC6A4DRD2SLC6A3DRD3 | |
| Oxalic Acid SCHEMBL10460865 | 0.83 | KMT2A (0.56) | DRD2MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL8809168 | 0.81 | HTR2A (0.60) | SLC6A2SLC6A4HRH3DRD3 | |
| Oxalic Acid SCHEMBL10459285 | 0.80 | HTR2A (0.49) | MEN1KMT2AKDM4EHRH3DRD3 | |
| Hydrochloric Acid SCHEMBL7406238 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4DRD2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |