Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466855 | 0.83 | HRH3 (0.71) | HTR2AHTR2CHTR7HRH3CYP2D6 | |
| SCHEMBL8809168 | 0.82 | HTR2A (0.60) | HTR2AHTR2CHTR7HRH3CYP2D6 | |
| SCHEMBL8805772 | 0.80 | DRD2 (0.61) | HTR2AHTR2CHTR7HRH3CYP2D6 | |
| SCHEMBL8808595 | 0.78 | HSD11B1 (0.58) | HTR2AHTR2CHTR7CYP2D6EPHX2 | |
| SCHEMBL10719633 | 0.77 | ALDH1A1 (0.55) | HTR2AHTR7HRH3HTR6 | |
| SCHEMBL10560195 | 0.77 | HTR1A (0.51) | HTR2AHTR7HRH3EPHX2HTR6 | |
| SCHEMBL10459423 | 0.76 | HRH3 (0.56) | HRH3 | |
| Hydrochloric Acid SCHEMBL7253239 | 0.76 | HTR2A (0.64) | HTR2AHTR2CHTR7HRH3CYP2D6 | |
| SCHEMBL8808110 | 0.76 | HTR2A (0.60) | HTR2AHTR2CHTR7HRH3CYP2D6 | |
| Water SCHEMBL10461590 | 0.76 | HRH3 (0.55) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751936-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025721-A1 | NEW 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS MEDICAMENTS ACTING ON THE GLUTAMATE RECEPTOR | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-09-28 | — | — | WO | disclosed |