Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20846588 | 0.84 | KDM4E (0.47) | USP2HRH3KMT2AMEN1RAB9A | |
| SCHEMBL8809493 | 0.74 | S1PR1 (0.56) | USP2HRH3KMT2ARAB9ALMNA | |
| SCHEMBL15104600 | 0.72 | NOTUM (0.51) | USP2CYP3A4CYP2D6CYP2C19RAB9A | |
| SCHEMBL24221657 | 0.72 | CACNA1G (0.58) | FTOKMT2AMEN1LMNAHTT | |
| SCHEMBL24093171 | 0.72 | HRH3 (0.86) | KDM1AHRH3KMT2AMEN1RAB9A | |
| SCHEMBL23200029 | 0.72 | USP2 (0.51) | USP2CYP2C9HRH3KMT2AMEN1 | |
| SCHEMBL8809487 | 0.72 | HRH3 (0.86) | KDM1AHRH3KMT2AMEN1RAB9A | |
| SCHEMBL24701101 | 0.72 | SOS1 (0.68) | HRH1KDM1ACYP2E1CYP3A4CYP2D6 | |
| SCHEMBL8807380 | 0.72 | HRH1 (0.62) | HRH1KDM1ACYP2E1CYP3A4CYP2D6 | |
| SCHEMBL1847296 | 0.71 | HRH3 (0.71) | HRH3KMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |