Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | FABP6 | P51161 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789534 | 1.00 | HRH3 (0.71) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL24574127 | 1.00 | HRH3 (0.71) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL294763 | 1.00 | HRH3 (0.71) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL11782513 | 0.98 | HRH3 (0.69) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL11781778 | 0.98 | HRH3 (0.69) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL433970 | 0.98 | GRIN2B (0.69) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Bromide SCHEMBL18131548 | 0.96 | HRH3 (0.67) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL11785266 | 0.96 | GRIN2B (0.67) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Methyl Alcohol SCHEMBL2137682 | 0.94 | HRH3 (0.65) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL4173336 | 0.94 | GRIN2B (0.69) | HRH3GRIN2BPOLBMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820573-B1 | 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF IKAROS FAMILY ZINC FINGER 2 (IKZF2)-DEPENDENT DISEASES | NOVARTIS AG (CH) | 2023-08-09 | — | — | EP | disclosed |
| EP-3363288-B1 | COMPOSITION FOR DESTRUCTION OF MICROALGAE OR MOSSES | CUREARTH INC (KR) | 2022-09-07 | — | — | EP | disclosed |
| CN-108347925-B | Compositions for destroying microalgae or moss | 株式会社CUREARTH | 2021-07-16 | — | — | CN | disclosed |
| US-11044909-B2 | Composition for destruction of microalgae or sphaerocarpus | CUREARTH, INC. (KR) | 2021-06-29 | — | — | US | disclosed |
| US-11044909-B2 | Composition for destruction of microalgae or sphaerocarpus | CUREARTH, INC. (KR) | 2021-06-29 | — | — | US | disclosed |
| WO-2020012334-A1 | 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF IKAROS FAMILY ZINC FINGER 2 (IKZF2)-DEPENDENT DISEASES | NOVARTIS AG (CH) | 2020-01-16 | — | — | WO | disclosed |
| US-20180271091-A1 | COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS | CUREARTH, INC. (KR) | 2018-09-27 | — | — | US | disclosed |
| EP-3363288-A1 | COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS | Curearth, Inc. (KR) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017065401-A1 | COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS | 주식회사 큐얼스 | 2017-04-20 | — | — | WO | disclosed |
| US-20110190511-A1 | Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto | IM&T RESEARCH, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| EP-2323974-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | Ube Industries, Ltd. (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20100152463-A1 | Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto | IM&T RESEARCH, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2010022001-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | IM&T RESEARCH, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| EP-0665216-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-12-29 | — | — | EP | disclosed |
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5576335-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0665216-A1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152463-A1 | Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto | PFAS, AGPS, FDPS | HRH3 3003/4885GRIN2B 3262/4885POLB 404/4885 |
| US-20110190511-A1 | Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto | PFAS, AGPS, FDPS | HRH3 4601/4885GRIN2B 2948/4885POLB 1165/4885 |
| US-20180271091-A1 | COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS | TK1, TRHDE, TK2 | HRH3 4196/4885GRIN2B 4263/4885POLB 1042/4885 |
| US-11044909-B2 | Composition for destruction of microalgae or sphaerocarpus | TK1, TRHDE, TK2 | HRH3 4196/4885GRIN2B 4263/4885POLB 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.