Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.58 |
| ▸ | EBP | Q15125 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 1/20 | 0.50 |
| ▸ | ATP4B | P51164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807859 | 0.96 | LTA4H (0.56) | LTA4HEBPSIGMAR1ESR1HRH3 | |
| SCHEMBL8810675 | 0.92 | LTA4H (0.58) | LTA4HESR1HRH3KCNH2ADORA2A | |
| SCHEMBL8808018 | 0.90 | ESR1 (0.61) | LTA4HESR1HRH3 | |
| SCHEMBL8810553 | 0.90 | LTA4H (0.52) | LTA4HESR1HRH3KCNH2ADORA2A | |
| SCHEMBL8810978 | 0.85 | ESR1 (0.66) | LTA4HESR1HRH3 | |
| SCHEMBL8809840 | 0.84 | LTA4H (0.56) | LTA4HEBPSIGMAR1ESR1HRH3 | |
| SCHEMBL8808818 | 0.84 | LTA4H (0.55) | LTA4HESR1HRH3KCNH2MCHR1 | |
| SCHEMBL10991494 | 0.81 | KDM4E (0.58) | ADORA2AADORA1 | |
| SCHEMBL10976797 | 0.81 | KDM4E (0.58) | ADORA2AADORA1 | |
| SCHEMBL8675943 | 0.81 | PTPN1 (0.56) | LTA4HESR1PTPN1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997004778-A1 | PYRIDINE COMPOUNDS, INTERMEDIATES, PROCESSES, COMPOSITIONS, AND METHODS | ELI LILLY AND COMPANY (US) | 1997-02-13 | — | — | WO | disclosed |