Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780694 | 0.82 | KDM4E (0.40) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL6785941 | 0.76 | GRIA1 (0.50) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9091481 | 0.66 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11326409 | 0.63 | SMN1; SMN2 (0.83) | KDM4ESMN1; SMN2 | |
| SCHEMBL17377711 | 0.62 | LMNA (0.57) | KDM4ESMN1; SMN2 | |
| SCHEMBL6781370 | 0.62 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL22442569 | 0.61 | HSD11B1 (0.34) | KDM4ESMN1; SMN2 | |
| SCHEMBL29566174 | 0.61 | KDM4E (0.38) | KDM4E | |
| SCHEMBL22442568 | 0.61 | KDM4E (0.38) | KDM4E | |
| SCHEMBL939954 | 0.60 | GRIK1 (0.73) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664807-B1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS | WARNER LAMBERT CO (US) | 1997-09-10 | — | — | EP | claimed |