Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999497 | 0.79 | RXFP1 (0.42) | ADORA3CYP19A1ADORA2AADORA2BADORA1 | |
| SCHEMBL27454303 | 0.76 | LMNA (0.43) | ADORA3CYP19A1ADORA2AADORA2BADORA1 | |
| SCHEMBL8803363 | 0.76 | NPC1 (0.50) | ADORA3CYP19A1ADORA2AADORA2BADORA1 | |
| SCHEMBL8804007 | 0.76 | LMNA (0.43) | ADORA3CYP19A1ADORA2AADORA2BADORA1 | |
| SCHEMBL8802832 | 0.76 | ADORA3 (0.55) | ADORA3CYP19A1ADORA2AADORA2BADORA1 | |
| SCHEMBL8812376 | 0.75 | MAPT (0.41) | CYP19A1MAPTLMNANPC1RAB9A | |
| SCHEMBL9867568 | 0.75 | ADORA3 (0.54) | ADORA3MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2213825 | 0.75 | ADORA3 (0.59) | ADORA3ADORA2AADORA2BADORA1LMNA | |
| SCHEMBL6531530 | 0.73 | CYP19A1 (0.62) | ADORA3CYP19A1ADORA2AADORA2BADORA1 | |
| SCHEMBL8802934 | 0.71 | GAA (0.40) | ADORA3CYP19A1ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751943-A1 | TRIAZOLE COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025107-A1 | TRIAZOLE COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1995-09-21 | — | — | WO | disclosed |