Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 6/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056936 | 0.86 | GAA (0.50) | ALDH1A1NPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL8809779 | 0.86 | GAA (0.52) | ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL8816831 | 0.85 | ALDH1A1 (0.46) | ALDH1A1BCL9CTNNB1HDAC1HDAC2 | |
| SCHEMBL8810690 | 0.83 | GAA (0.46) | ALDH1A1NPSR1GAABCL9CTNNB1 | |
| SCHEMBL8817749 | 0.83 | NPSR1 (0.49) | ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL8808422 | 0.83 | TP53 (0.52) | ALDH1A1NPSR1GAALMNA | |
| SCHEMBL8807180 | 0.83 | GAA (0.49) | ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL8808845 | 0.83 | GAA (0.51) | ALDH1A1NPSR1GAA | |
| SCHEMBL8809768 | 0.82 | GAA (0.48) | ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL8807120 | 0.82 | GAA (0.48) | ALDH1A1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |