Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811224 | 0.84 | PPARG (0.47) | PPARGFFAR1TSHRMAPTCA2 | |
| SCHEMBL8685774 | 0.82 | FFAR1 (0.50) | PPARGFFAR1MAPTCA2HTR6 | |
| SCHEMBL8685815 | 0.81 | FFAR1 (0.45) | PPARGFFAR1CNR2CNR1CA2 | |
| SCHEMBL8685077 | 0.81 | PPARG (0.42) | HRH3PPARGFFAR1CNR1TSHR | |
| SCHEMBL8810162 | 0.80 | PPARG (0.44) | PPARGFFAR1MAPTCA2KCNH2 | |
| SCHEMBL8810514 | 0.80 | PPARG (0.46) | PPARGFFAR1CNR2CNR1MAPT | |
| SCHEMBL8809561 | 0.80 | FFAR1 (0.48) | HRH3PPARGFFAR1MAPTCA2 | |
| SCHEMBL8685380 | 0.79 | CA2 (0.43) | HRH3PPARGFFAR1MAPTCA2 | |
| SCHEMBL8810551 | 0.79 | PPARG (0.48) | HRH3PPARGFFAR1MAPTHTR6 | |
| SCHEMBL8685830 | 0.79 | PPARG (0.47) | PPARGFFAR1MAPTCA2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |