Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810780 | 0.89 | PARP1 (0.66) | PARP1SMN1; SMN2ALDH1A1LMNASIRT1 | |
| SCHEMBL8809347 | 0.89 | PARP1 (1.00) | PARP1SMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL8809350 | 0.89 | PARP1 (1.00) | PARP1SMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL8811389 | 0.89 | PARP1 (0.62) | PARP1SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL8812789 | 0.87 | SMN1; SMN2 (0.62) | PARP1SMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL8685538 | 0.86 | PARP1 (0.63) | PARP1SMN1; SMN2ALDH1A1LMNASIRT1 | |
| SCHEMBL8809776 | 0.85 | PARP1 (0.64) | PARP1SMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL8811136 | 0.85 | PARP1 (0.58) | PARP1SMN1; SMN2ALDH1A1LMNASIRT1 | |
| SCHEMBL8810237 | 0.83 | PARP1 (0.61) | PARP1SMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL8809713 | 0.83 | PARP1 (0.63) | PARP1SMN1; SMN2ALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |