Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685971 | 1.00 | PARP1 (0.58) | PARP1AKR1B1PIM1PIM2GSK3B | |
| SCHEMBL8810069 | 0.93 | PARP1 (0.54) | PARP1AKR1B1PIM1PIM2GSK3B | |
| SCHEMBL8810062 | 0.93 | PARP1 (0.54) | PARP1AKR1B1PIM1PIM2GSK3B | |
| SCHEMBL8691075 | 0.90 | PARP1 (0.60) | PARP1AKR1B1PIM1PIM2GSK3B | |
| SCHEMBL8808793 | 0.90 | PARP1 (0.60) | PARP1AKR1B1PIM1PIM2GSK3B | |
| SCHEMBL8809369 | 0.89 | SLC2A1 (0.46) | PARP1AKR1B1PIM1PIM2SLC2A1 | |
| SCHEMBL8810629 | 0.89 | PARP1 (0.74) | PARP1AKR1B1PIM1PIM2GSK3B | |
| SCHEMBL8690307 | 0.89 | PARP1 (0.74) | PARP1AKR1B1PIM1PIM2GSK3B | |
| SCHEMBL8685371 | 0.88 | PARP1 (0.62) | PARP1AKR1B1PIM1PIM2SLC2A1 | |
| SCHEMBL8809167 | 0.88 | PARP1 (0.62) | PARP1AKR1B1PIM1PIM2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |