Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810062 | 1.00 | PARP1 (0.54) | PARP1GSK3BAKR1B1PIM1PIM2 | |
| SCHEMBL8809361 | 0.93 | PARP1 (0.58) | PARP1GSK3BAKR1B1PIM1PIM2 | |
| SCHEMBL8685971 | 0.93 | PARP1 (0.58) | PARP1GSK3BAKR1B1PIM1PIM2 | |
| SCHEMBL8808793 | 0.91 | PARP1 (0.60) | PARP1GSK3BAKR1B1PIM1PIM2 | |
| SCHEMBL8691075 | 0.91 | PARP1 (0.60) | PARP1GSK3BAKR1B1PIM1PIM2 | |
| SCHEMBL8810078 | 0.88 | CSNK2A2 (0.45) | PARP1GSK3BAKR1B1PIM1PIM2 | |
| SCHEMBL8810794 | 0.87 | PARP1 (0.55) | PARP1PIM1PIM2GSK3AMEN1 | |
| SCHEMBL8810800 | 0.87 | PARP1 (0.55) | PARP1PIM1PIM2GSK3AMEN1 | |
| SCHEMBL8813162 | 0.85 | GSK3B (0.51) | PARP1GSK3BAKR1B1PIM1PIM2 | |
| SCHEMBL8813157 | 0.85 | GSK3B (0.51) | PARP1GSK3BAKR1B1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |