Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594920 | 0.81 | MAPT (0.56) | ALDH1A1MAPTGAAL3MBTL1MAOB | |
| SCHEMBL29502955 | 0.81 | MAPT (0.56) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1061802 | 0.81 | MAPT (0.56) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL21083437 | 0.80 | MAOB (0.55) | L3MBTL1PARP15PARP10MAOBSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28855632 | 0.80 | MAPT (0.55) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1577994 | 0.78 | MAPT (0.52) | ALDH1A1MAPTGAAL3MBTL1MAOB | |
| SCHEMBL31504334 | 0.77 | MAOB (0.56) | MAPTPARP15PARP10MAOBNPC1 | |
| SCHEMBL4337519 | 0.77 | MAOB (0.56) | MAPTPARP15PARP10MAOBNPC1 | |
| SCHEMBL30764792 | 0.77 | HSPB1 (0.55) | ALDH1A1MAPTL3MBTL1PARP10SMN1; SMN2 | |
| SCHEMBL15411721 | 0.77 | MAPT (0.53) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782570-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009294-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |