Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809666 | 0.89 | PTGIR (0.59) | PTGIR | |
| SCHEMBL8813608 | 0.89 | PTGIR (0.59) | PTGIR | |
| SCHEMBL8411295 | 0.88 | PTGIR (0.44) | PTGIRABCB1SIGMAR1HTR1A | |
| SCHEMBL8812537 | 0.85 | PTGIR (0.39) | PTGIRKLKB1 | |
| SCHEMBL8812532 | 0.85 | PTGIR (0.39) | PTGIRKLKB1 | |
| SCHEMBL8809050 | 0.80 | CYP19A1 (0.38) | PTGIRABCB1SIGMAR1HTR1ACNR1 | |
| SCHEMBL8812368 | 0.77 | PTGIR (0.67) | PTGIRKLKB1 | |
| SCHEMBL8810992 | 0.77 | PTGIR (0.57) | PTGIRSIGMAR1HTR1A | |
| SCHEMBL8411294 | 0.77 | PTGIR (0.57) | PTGIRSIGMAR1HTR1A | |
| SCHEMBL8811344 | 0.75 | PTGIR (0.68) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |