Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808039 | 0.97 | MLNR (0.34) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL8807004 | 0.93 | MLNR (0.41) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL8806664 | 0.82 | MLNR (0.57) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL8806637 | 0.82 | MGLL (0.45) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL3632231 | 0.80 | HTR2B (0.40) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL8805739 | 0.80 | HTR2B (0.40) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL8807657 | 0.80 | HTR2B (0.40) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL6959300 | 0.80 | MLNR (0.44) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL8805622 | 0.80 | MLNR (0.44) | MLNRNR1I2ABCB11PGRCTSD | |
| SCHEMBL8806962 | 0.79 | MLNR (0.43) | MLNRNR1I2ABCB11PGRCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758327-A1 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-19 | — | — | EP | disclosed |