Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.50 |
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407710 | 0.90 | CAPN1 (0.47) | CAPN1CTSKCTSLCTSSCASP1 | |
| SCHEMBL8811002 | 0.89 | CAPN1 (0.48) | CAPN1CTSKCTSLCTSSCASP1 | |
| SCHEMBL8808872 | 0.89 | CTSK (0.43) | CAPN1CTSKCTSLCTSSCASP1 | |
| SCHEMBL8404287 | 0.89 | CAPN1 (0.51) | CAPN1CTSKCTSLCTSSCASP1 | |
| SCHEMBL8812425 | 0.84 | CAPN1 (0.53) | CAPN1CTSKCTSLCTSSALDH1A1 | |
| SCHEMBL8809740 | 0.84 | CAPN1 (0.68) | CAPN1CTSKCTSLCTSSCAPNS1 | |
| SCHEMBL8809749 | 0.84 | CAPN1 (0.68) | CAPN1CTSKCTSLCTSSCAPNS1 | |
| SCHEMBL8810857 | 0.82 | CAPN1 (0.49) | CAPN1CASP1CASP3CASP7CASP6 | |
| SCHEMBL8807293 | 0.81 | CAPN1 (0.42) | CAPN1CAPNS1 | |
| SCHEMBL8810844 | 0.80 | SMN1; SMN2 (0.39) | CAPN1SMN1; SMN2CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |