Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564272 | 0.99 | AGTR1 (0.41) | AGTR1LTB4R2PTGDR2ABCB11GP6 | |
| SCHEMBL8812951 | 0.98 | AGTR1 (0.40) | AGTR1LTB4R2PTGDR2ABCB11GP6 | |
| SCHEMBL8811670 | 0.95 | AGTR1 (0.36) | AGTR1LTB4R2PTGDR2ABCB11GP6 | |
| SCHEMBL8811985 | 0.93 | AGTR1 (0.39) | AGTR1LTB4R2PTGDR2ABCB11GP6 | |
| SCHEMBL8812419 | 0.93 | OPRM1 (0.34) | AGTR1PTGDR2 | |
| SCHEMBL7278225 | 0.92 | AGTR1 (0.49) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8813693 | 0.90 | AGTR1 (0.32) | AGTR1AGTR2 | |
| SCHEMBL8809429 | 0.89 | AGTR1 (0.36) | AGTR1LTB4R2PTGDR2AGTR2PKM | |
| SCHEMBL8811459 | 0.89 | AGTR1 (0.32) | AGTR1AGTR2 | |
| SCHEMBL8482137 | 0.89 | AGTR1 (0.43) | AGTR1LTB4R2PTGDR2ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528762-B1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | claimed |
| EP-0528762-A1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA-GEIGY AG (CH) | 1993-02-24 | — | — | EP | claimed |
| EP-0528762-B1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| EP-0528762-A1 | N-acyl-N-heterocyclyl- or naphthyl-alkyl amino acids as angiotensin II antagonists | CIBA-GEIGY AG (CH) | 1993-02-24 | — | — | EP | disclosed |