Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | GPR18 | Q14330 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809966 | 1.00 | AKR1B1 (0.49) | AKR1B1MMP3MMP13TLR4TLR2 | |
| Hydrochloric Acid SCHEMBL8807981 | 0.99 | AKR1B1 (0.48) | AKR1B1MMP3MMP13TLR4TLR2 | |
| Hydrochloric Acid SCHEMBL8807977 | 0.99 | AKR1B1 (0.48) | AKR1B1MMP3MMP13TLR4TLR2 | |
| SCHEMBL27510350 | 0.81 | CYP1A2 (0.42) | MAOBLMNAMAPTALDH1A1HPGD | |
| SCHEMBL1889059 | 0.79 | EGFR (0.50) | AKR1B1MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL1889060 | 0.79 | EGFR (0.50) | AKR1B1MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL1009494 | 0.76 | AKR1B1 (0.51) | AKR1B1MMP3MMP13TLR4TLR2 | |
| SCHEMBL2258288 | 0.76 | CYP1A2 (0.41) | MAOBLMNAMAPTALDH1A1HPGD | |
| SCHEMBL2261719 | 0.76 | CYP1A2 (0.41) | MAOBLMNAMAPTALDH1A1HPGD | |
| SCHEMBL27503792 | 0.75 | HSD11B1 (0.50) | MAOBMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532767-B1 | 3-Phenoxybenzyl(idene)pyrrolidine derivatives, their preparation and their use as muscarinic cholinergic agents | KANEGAFUCHI CHEMICAL IND (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5270339-A | Phenoxybenzene derivative | KANAGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0532767-A1 | 3-Phenoxybenzyl(idene)pyrrolidine derivatives, their preparation and their use as muscarinic cholinergic agents | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-03-24 | — | — | EP | disclosed |