Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810163 | 0.92 | MRGPRX4 (0.41) | MEN1ALDH1A1GAAKMT2AMRGPRX4 | |
| SCHEMBL8808406 | 0.85 | MRGPRX4 (0.41) | MRGPRX4 | |
| SCHEMBL8809995 | 0.78 | MEN1 (0.43) | MEN1ALDH1A1GAAKMT2AMRGPRX4 | |
| SCHEMBL8808917 | 0.75 | XDH (0.45) | FNTAFNTBPGGT1BMRGPRX4 | |
| SCHEMBL8809211 | 0.74 | MAOB (0.54) | MRGPRX4 | |
| SCHEMBL8814947 | 0.73 | AR (0.40) | PDE4BMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL8810273 | 0.73 | MRGPRX4 (0.43) | MRGPRX4 | |
| SCHEMBL8807149 | 0.73 | NPC1 (0.48) | MEN1KMT2AMRGPRX4 | |
| SCHEMBL8808922 | 0.72 | FFAR1 (0.44) | MRGPRX4 | |
| SCHEMBL8807665 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805802-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE-POULENC RORER LIMITED (GB) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022978-A1 | SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS | RHONE POULENC RORER LIMITED (GB) | 1996-08-01 | — | — | WO | disclosed |