Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.57 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.57 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.57 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 9/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786083 | 0.78 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4PSMB5 | |
| SCHEMBL6789366 | 0.76 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL6781370 | 0.73 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL20571761 | 0.69 | PSMB5 (0.49) | GRIA1GRIA2GRIA3GRIA4PSMB5 | |
| Hydrochloric Acid SCHEMBL30529512 | 0.68 | PSMB5 (0.48) | GRIA1GRIA2GRIA3GRIA4PSMB5 | |
| SCHEMBL4929162 | 0.67 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PSMB5 | |
| SCHEMBL6780605 | 0.66 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL7420610 | 0.66 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4PSMB5 | |
| SCHEMBL12068243 | 0.66 | UHRF1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9919035 | 0.66 | DRD1 (0.41) | GRIA1GRIA2GRIA3GRIA4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664807-B1 | QUINOXALINEDIONE DERIVATIVES AS EAA ANTAGONISTS | WARNER LAMBERT CO (US) | 1997-09-10 | — | — | EP | claimed |