Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602982 | 0.88 | HDAC1 (0.41) | KDM4EIGF1RALOX15MEN1ALDH1A1 | |
| SCHEMBL8602980 | 0.88 | HDAC1 (0.41) | KDM4EIGF1RALOX15MEN1ALDH1A1 | |
| SCHEMBL3871113 | 0.87 | IDH1 (0.51) | ALOX15KDM5AKDM5BPKM | |
| SCHEMBL8600012 | 0.80 | LMNA (0.44) | ALDH1A1LMNAMAPTSLC6A2PTGS2 | |
| SCHEMBL15483500 | 0.80 | RECQL (0.44) | KDM4EALOX15LMNAMAPT | |
| SCHEMBL11061990 | 0.78 | TRPA1 (0.47) | KDM4EALOX15MEN1ALDH1A1POLB | |
| SCHEMBL311094 | 0.77 | CYP3A4 (0.58) | KDM4EMEN1LMNAMAPTRAB9A | |
| SCHEMBL30153587 | 0.77 | CYP3A4 (0.58) | KDM4EMEN1LMNAMAPTRAB9A | |
| SCHEMBL8601117 | 0.77 | KAT8 (0.48) | KDM4EALDH1A1LMNAADORA3CHRM1 | |
| SCHEMBL13369864 | 0.76 | KDM4E (0.42) | KDM4EMEN1ALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |