Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810562 | 1.00 | MMP1 (0.43) | MMP1MMP9CASP3KMT2ASENP8 | |
| SCHEMBL8810870 | 1.00 | MMP1 (0.43) | MMP1MMP9CASP3KMT2ASENP8 | |
| SCHEMBL8807239 | 0.86 | MMP1 (0.43) | MMP1MMP9ELANERXFP1 | |
| SCHEMBL2923216 | 0.86 | MMP1 (0.43) | MMP1MMP9ELANERXFP1 | |
| SCHEMBL8807243 | 0.86 | MMP1 (0.43) | MMP1MMP9ELANERXFP1 | |
| SCHEMBL7172605 | 0.86 | MMP1 (0.43) | MMP1MMP9ELANERXFP1 | |
| SCHEMBL8888422 | 0.86 | MMP1 (0.43) | MMP1MMP9ELANERXFP1 | |
| SCHEMBL9384795 | 0.78 | ELANE (0.44) | MMP1MMP9ELANE | |
| SCHEMBL8809346 | 0.77 | MMP9 (0.43) | MMP1MMP9CASP3KMT2ASENP8 | |
| SCHEMBL8806989 | 0.76 | MMP1 (0.42) | MMP1MMP9RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232966-B1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| EP-0232966-A1 | Process for the preparation of penem compounds and intermediates for this preparation | BEECHAM GROUP PLC (GB) | 1987-08-19 | — | — | EP | disclosed |